Scheme Information Sheets

UK NEQAS for Quantitative Amino Acids

Scheme Particulars Indicative Details
Accreditation body UKAS
ISO/IEC Accreditation status ISO/IEC 17043:2010
UKAS Accredited Proficiency Testing Provider No 7860
Objective of Scheme Provides EQA coverage and analytical assessment for Amino Acid assays used in the investigation of metabolic disorders in both Paedetaric and adult patients. The Scheme distributes a number of manipulated specimens covering a wide concentration range for Phenylalanine, Tyrosine, Leucine, Isoleucine and Valine
Pre-, Analytical, Post- status Analytical
Number of distributions per year (nominal) 11
Specimens per distribution 3
Number of Specimens per annum 33
Frequency of distribution Monthly
Scoring system ABC
Material distributed Pooled, liquid human serum with or without exogenous added analyte
Programme Director(s) / Organiser(s) Finlay MacKenzie
Criteria for participation All, but overseas by courier
Nominal sample volume (mL) 1
Sample presentation TACs All analytes in the same tube
Data in Chemistry on-line Dashboard Yes
Analyte Approx Range Default Units Target Value B Score Limit (%) C Score Limit (%)
Isoleucine 40 – 1000 µmol/L ALTM 10.0 15.0
Leucine 60 – 1000 µmol/L ALTM 10.0 15.0
Phenylalanine 40 – 1400 µmol/L ALTM 10.0 15.0
Tyrosine 40 – 800 µmol/L ALTM 10.0 15.0
Valine 100 – 1000 µmol/L ALTM 10.0 15.0
Abbreviation Expansion
ALTM All Laboratory Trimmed Mean
GLTM Group Laboratory Trimmed Mean – which is the Method Principle Mean
MLTM Method Laboratory Trimmed Mean – usually a manufacturer system / analyser mean
XALTM An external value that may be from a Reference Method System
OGLTM A Method Principle Mean used as the target for all laboratories
OMLTM A specific Method Mean used as a target for all laboratories
MED Median

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