Scheme Information Sheets

UK NEQAS for Clinical Chemistry

Scheme Particulars Indicative Details
Accreditation body UKAS
ISO/IEC Accreditation status ISO/IEC 17043:2010
UKAS Accredited Proficiency Testing Provider No 7860
Objective of Scheme Provides EQA coverage for a large number of routine analytes found on a clinical chemistry analyser. This includes tests for electrolytes, renal and liver function.

The Scheme distributes a number of endogenous and manipulated specimens to allow a comprehensive range of concentrations to be achieved.
Birmingham Quality has a number of other EQA Schemes which allow specimens to be more targetted at specific concentrations for specific clinical conditions. For example the UK NEQAS for Paediatric bilirubin Scheme which covers higher concentrations of bilirubin which would ordinarily interfere with some analytes in the UK NEQAS for Clinical Chemistry Scheme
Pre-, Analytical, Post- status Analytical
Number of distributions per year (nominal) 22
Specimens per distribution 3
Number of Specimens per annum 66
Frequency of distribution Fortnightly
Scoring system ABC
Material distributed Pooled, liquid human serum with or without exogenous added analyte
Programme Director(s) / Organiser(s) Finlay MacKenzie
Criteria for participation All, but overseas by courier
Nominal sample volume (mL) 1
Sample presentation TACs All analytes in the same tube
Data in Chemistry on-line Dashboard Yes
Analyte Approx Range Default Units Target Value B Score Limit (%) C Score Limit (%)
Adjusted calcium 0.8 – 4 mmol/L GLTM 3.0 4.0
Albumin 32 – 58 g/L GLTM 5.0 4.0
ALP [Alk Phos] 20 – 440 U/L MLTM 10.0 7.5
ALT [ALAT] 5 – 80 U/L MLTM 7.5 10.0
Amylase 40 – 600 U/L MLTM 7.5 7.5
Anion Gap 0 – 50 mmol/L ALTM 15.0 20.0
AST [ASAT] 10 – 100 U/L MLTM 7.5 10.0
Bicarbonate 3 – 35 mmol/L ALTM 15.0 15.0
Bilirubin 0 – 240 µmol/L ALTM 20.0 15.0
Calcium 1 – 4 mmol/L ALTM 3.0 4.0
Chloride 90 – 140 mmol/L ALTM 3.0 2.5
CK 4 – 360 U/L MLTM 7.5 7.5
Copper 0 – 30 µmol/L ALTM 15.0 20.0
Creatinine 30 – 450 µmol/L OGLTM 6.0 10.0
D-3-hydroxybutyrate 30 – 1200 µmol/L ALTM 20.0 15.0
FIB-4 0.5 – 6.0 ~ MLTM 7.5 10.0
GGT 12 – 500 U/L MLTM 7.5 7.5
Globulins 0 – 50 g/L ALTM 7.5 10.0
Glucose 1.8 – 32 mmol/L ALTM 4.0 5.0
Iron 2 – 24 µmol/L ALTM 7.5 7.5
Lactate 0.5 – 10 mmol/L ALTM 7.5 7.5
LD 75 – 500 U/L MLTM 10.0 10.0
Lipase 40 – 650 U/L MLTM 10.0 15.0
Lithium 0 – 1.3 mmol/L ALTM 10.0 15.0
Magnesium 0.4 – 1.8 mmol/L ALTM 4.0 5.0
Osmolal Gap 0 – 20 mmol/kg XALTM 100.0 150.0
Osmolality 260 – 480 mmol/kg ALTM 2.0 2.0
Phosphate 0 – 2 mmol/L ALTM 5.0 5.0
Potassium 2 – 10 mmol/L ALTM 2.0 2.5
Sodium 115 – 185 mmol/L ALTM 1.5 2.0
TIBC 20 – 90 µmol/L ALTM 15.0 15.0
Total protein 48 – 100 g/L ALTM 5.0 4.0
Transferrin 0 – 5 g/L ALTM 7.5 10.0
Transferrin Saturation 0 – 100 % ALTM 15.0 10.0
UIBC 20 – 90 µmol/L ALTM 15.0 15.0
Urate 90 – 700 µmol/L ALTM 4.0 4.0
Urea 1 – 50 mmol/L ALTM 5.0 5.0
Zinc 4 – 32 µmol/L ALTM 15.0 20.0

Analyte not yet accredited to ISO/IEC 17043:2010

Abbreviation Expansion
ALTM All Laboratory Trimmed Mean
GLTM Group Laboratory Trimmed Mean – which is the Method Principle Mean
MLTM Method Laboratory Trimmed Mean – usually a manufacturer system / analyser mean
XALTM An external value that may be from a Reference Method System
OGLTM A Method Principle Mean used as the target for all laboratories
OMLTM A specific Method Mean used as a target for all laboratories
MED Median

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